Menopause and metabolism: don't let it slow you down

Clarice P.
Health
May 1, 2025
3 minutes

Menopause isn’t just a hormonal change—it’s a profound transition that affects the body, mind, and metabolism. Many women suddenly find themselves dealing with unexplained weight gain, a shift in fat distribution, increased fatigue, and a general feeling of “not recognizing themselves anymore.” But what is really happening to metabolism during menopause? And what can we do to care for our health in a tangible, effective way?

In this article, we dive into the latest scientific evidence to better understand the mechanisms behind metabolic changes in menopause and offer practical strategies to navigate them.

1. Your metabolism slows down—but it's not your fault

As we age, our basal metabolic rate decreases by about 2–4% per decade. During menopause, this process accelerates due to muscle loss (sarcopenia) and declining estrogen levels. Recent studies (Nature, 2023) confirm that women in menopause lose up to 1% of lean mass each year, directly impacting resting energy expenditure.

What does this mean? Even if your diet and activity levels stay the same, you may gain weight more easily. It’s not about willpower—it’s about biology.

2. Fat shifts location: say hello to visceral fat

Even if your weight doesn’t change, your fat distribution likely will. Estrogen decline promotes the accumulation of visceral fat—especially abdominal fat—which is metabolically active and produces inflammatory cytokines such as TNF-α and IL-6.

Why it matters: This type of fat increases the risk of insulin resistance, diabetes, hypertension, and cardiovascular disease. According to the American Heart Association (2023), abdominal fat can increase by up to 20% during menopause—even in women of normal weight.

3. Increased risk of insulin resistance and type 2 diabetes

Estrogens play a key role in regulating glucose metabolism. Their absence reduces the effectiveness of the GLUT4 transporter in muscles, limiting glucose absorption and causing blood sugar levels to rise.

The result? Postmenopausal women have twice the risk of developing type 2 diabetes, with fasting glucose levels averaging 8 mg/dL higher than premenopausal women.

4. Poor sleep makes everything worse

Sleep is a natural metabolic regulator. In menopause, sleep disturbances are common and linked to hormonal fluctuations, night sweats, anxiety, and stress. Poor sleep alters the production of leptin and ghrelin—hormones that control hunger and satiety.

What happens: You feel hungrier, crave sugary foods, and have less energy for exercise. A cycle that’s hard to break without awareness and support.

5. The risk of chronic disease rises

Menopause is an independent risk factor for several chronic diseases:

  • Cardiovascular disease: +50% risk in the first 10 years post-menopause
  • Osteoporosis: 2–3% annual bone loss in the first 5 years
  • Cognitive decline: reduced cerebral blood flow and increased beta-amyloid accumulation, linked to Alzheimer’s

These facts shouldn’t scare us—they should motivate us to care for ourselves with evidence-based tools and compassion.

What you can do: practical strategies to support your metabolism

🧘‍♀️ Move regularly and build muscle mass

  • Strength training 2–3 times per week
  • Daily walking, pilates, yoga, or swimming

🥗 Nourish your body smartly

  • Increase protein intake (1.2–1.5 g/kg of body weight)
  • Choose healthy fats (extra virgin olive oil, nuts)
  • Supplement vitamin D and calcium if needed

🧠 Manage stress

  • Meditation, deep breathing, journaling
  • Just a few minutes a day makes a difference

📊 Monitor your health markers

  • Waist circumference, blood pressure, glucose, HOMA-IR
  • Talk to your doctor for a personalized assessment

🤝 Seek support You are not alone. Medical and multidisciplinary care pathways can support you through this stage with science, empathy, and personalization.

Menopause is not a metabolic sentence—it’s a phase of transformation. Understanding what’s happening in your body is the first step to taking care of yourself with awareness. With the right strategies, it’s possible to protect your metabolism, prevent chronic diseases, and live this new stage of life with energy, balance, and confidence.


💛 At Pausetiv, we’re here to help you do just that.



Sources:

  • Circulation, Nature, Cell Metabolism, Sleep Medicine Reviews, Journal of Bone and Mineral Research, Neurology (2020–2023).